专利名称：Benzonatate modified release solid tablets
and capsules
发明人：Andrea Nelson,Quin-Zene Chen,Harsh
Mehta,Yu-Hsing Tu
申请号：US15075697申请日：20160321公开号：US09867797B2公开日：20180116
摘要：A 12-hour anti-tussive modified release solid tablet or capsule is describedwhich comprises a benzonatate adsorbate in a matrix with a sufficient amount of one ormore pharmaceutically acceptable modified release pH-independent, substances toprovide a 12-hour modified release profile to the benzonatate, wherein there is
substantially no benzonatate release from the tablet or capsule in the buccal cavity andno more than about 25% release of the benzonatate within 1 hour as determined in an invitro dissolution assay.
申请人：TRIS Pharma Inc.
地址：Monmouth Junction NJ US
国籍：US
代理机构：Howson and Howson LLP
代理人：Cathy A. Kodroff,Egon Berg
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