Product Data SheetProduct Name:CAS No.: CatNo:Cat. No.:MWt:Formula:Purity :Bacitracin Zinc1405-89-6HY-B02781486.06C66H101N17O16SZn>98%Solubility:DMSO<1mg/mL;Water<1mg/mLDMSO <1 mg/mL; Water <1 mg/mLMechanisms: Pathways:Anti-infection; Target:Antibacterial Biological Activity:Bacitracin Zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibitionof cleavage of Tyr from Met-enkephalin with IC50 of 10 μM. Target: Antibacterial Bacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformisgroup of Bacillus subtilis var Tracy. Its unique name derives from the fact that the bacillus producingit was first isolated in 1943 from a knee scrape from a girl named Margaret Tracy. As a toxic anddifficult-to-use antibiotic, bacitracin doesn't work well orally. However, it is very effective topically.Bacitracin is synthesised via the so-called nonribosomal peptide synthetases (NRPSs), whichmeansthatribosomesarenotinvolvedinitssynthesis[12] means that ribosomes are not involved in its synthesis [1, 2]....References:[1]. Murphy, T., et al., Effect of oligosaccharide elicitors on bacitracin A production and evidence oftranscriptional level control. J Biotechnol, 2007. 131(4): p. 397-403. [2]. Karala, A.R. and L.W. Ruddock, Bacitracin is not a specific inhibitor of protein disulfideisomeraseFEBSJ2010277(11):p245462 isomerase. FEBS J, 2010. 277(11): p. 2454-62.Caution: Not fully tested. For research purposes onlyMedchemexpress LLCwww.medchemexpress.com 18 Wilkinson Way, Princeton, NJ 08540,USAess.com Web: www.medchemexpress.comEmail: info@medchemexpr