ANIMAL WITH THE MASS EXPRESSION OF HUMAN GENE AND

专利名称：ANIMAL WITH THE MASS EXPRESSION OF

HUMAN GENE AND TEST METHOD BYUSING THE ANIMAL

发明人：URADE, YOSHIHIRO,FUJITANI,

YASUSHI,KITAYAMA, HIROAKI,HAYASHI,NAOKI

申请号：EP00964699申请日：20001005公开号：EP1224861A4公开日：20041208

摘要：The present application provides a human gene over-expressing animal, which isa non-human animal carrying a human hematopoietic prostaglandin D synthase gene in itssomatic cell chromosome and expressing a large amount of human prostaglandin Dsynthase, wherein the animal is one obtained through ontogenesis of a totipotency cellof a non-human animal or offspring of the obtained animal, and the totipotency cell isintroduced with said synthase gene. The present application also provides a method ofusing the transgenic animal for testing activity of a candidate for anti-allergy medicines,sleep-controlling substances and candidates for anti-obesity.

申请人：JAPAN SCIENCE AND TECHNOLOGY AGENCY,OSAKA BIOSCIENCEINSTITUTE,ORIENTAL YEAST CO., LTD.

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