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ARYL-SUBSTITUTED BENZO[D]ISOTHIAZOL-3-YLAMINE ANAL

2022-07-03 来源:客趣旅游网
专利内容由知识产权出版社提供

专利名称:ARYL-SUBSTITUTED BENZO[D]ISOTHIAZOL-3-YLAMINE ANALOGUES AS CAPSAICINRECEPTOR MODULATORS

发明人:BLUM, Charles, A.,ZHENG, Xiazhang申请号:EP04786051.5申请日:20040709公开号:EP1648892B1公开日:20070620

摘要:Aryl-substituted benzo[d]isothiazol-3-ylamine analogues are provided, of theFormula (I): wherein variables are as described herein. Such compounds are ligands thatmay be used to modulate capsaicin in vivo or in vitro, and are particularly useful in thetreatment of conditions associated with pathological capsaicin receptor activation inhumans, domesticated companion animals and livestock animals. Pharmaceuticalcompositions and methods for using such compounds to treat such disorders areprovided, as are methods for using such ligands for receptor localization studies.

申请人:NEUROGEN CORP

地址:US

国籍:US

代理机构:Forstmeyer, Dietmar

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