TRANSISTOR-BASED BIOSENSORS HAVING GATE ELECTRODES

专利名称：TRANSISTOR-BASED BIOSENSORS HAVING

GATE ELECTRODES COATED WITHRECEPTOR MOLECULES

发明人：YITZCHAIK, Shlomo,SPIRA, Micha,7 Malki

Street,SHAPPIR, Joseph

申请号：EP03811052.4申请日：20031111公开号：EP1561100A1公开日：20050810

摘要：A device and method are presented for detecting analyte molecules in amedium. At least one FET (Field Effect Transistor) is provided being formed by at leastone pair of source-drain electrodes and at least one gate electrode. The gate electrodeis coated with a layer of receptor molecules that in the presence of said analytes catalyzea reaction that causes release of ions in a medium surrounding said receptor molecules. Amonolayer of linker molecules is provided for linking said receptor molecules to said atleast one gate such that a distance between the receptor molecules layer and thesurface of the coated gate is smaller than 15A. In the prefered embodiments, thereceptor molecules are enzymes (e.g. acetylcholine estarase) or peptides, and theanalyte molecules are pesticides, herbicides and chemical pollutants of industrial origin.

申请人：YISSUM RESEARCH DEVELOPMENT COMPANYOF THE HEBREW UNIVERSITYOF JERUSALEM

地址：Hi Tech Park,Edmond Safra CampusGivat Ram 91390 Jerusalem IL

国籍：IL

代理机构：Verdure, Stéphane

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