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METHOD AND COMPOSITIONS FOR INDUCING DIFFERENTIATI

2022-11-12 来源:客趣旅游网
专利内容由知识产权出版社提供

专利名称:METHOD AND COMPOSITIONS FOR

INDUCING DIFFERENTIATION OF MYELOIDDERIVED SUPPRESSOR CELL TO TREATCANCER AND INFECTIOUS DISEASES

发明人:POIRIER, Nicolas,VANHOVE, Bernard申请号:EP15794641.9申请日:20151021公开号:EP3209691A1公开日:20170830

摘要:The present invention pertains to the field of immunotherapy. More specifically,the present invention provides a method for differentiating myeloid-derived suppressorcells (MDSC) into non suppressive cells, by administering a compound blocking theinteraction between SIRPa and CD47 to a patient in need thereof, in order to reduceMDSC-induced immunodepression and consequently allow appropriate immuneresponses in cancers, infectious diseases, vaccination, trauma, autoimmune diseases,chronic inflammatory diseases and transplantation.

申请人:OSE Immunotherapeutics

地址:22 Boulevard Benoni Goullin 44200 Nantes FR

国籍:FR

代理机构:Gevers & Orès

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