专利名称:METHOD AND COMPOSITIONS FOR
INDUCING DIFFERENTIATION OF MYELOIDDERIVED SUPPRESSOR CELL TO TREATCANCER AND INFECTIOUS DISEASES
发明人:POIRIER, Nicolas,VANHOVE, Bernard申请号:EP15794641.9申请日:20151021公开号:EP3209691A1公开日:20170830
摘要:The present invention pertains to the field of immunotherapy. More specifically,the present invention provides a method for differentiating myeloid-derived suppressorcells (MDSC) into non suppressive cells, by administering a compound blocking theinteraction between SIRPa and CD47 to a patient in need thereof, in order to reduceMDSC-induced immunodepression and consequently allow appropriate immuneresponses in cancers, infectious diseases, vaccination, trauma, autoimmune diseases,chronic inflammatory diseases and transplantation.
申请人:OSE Immunotherapeutics
地址:22 Boulevard Benoni Goullin 44200 Nantes FR
国籍:FR
代理机构:Gevers & Orès
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