专利名称:PURIFICATION OF STREPTOCOCCAL
CAPSULAR POLYSACCHARIDE
发明人:COSTANTINO, PAOLO申请号:EP06710574.2申请日:20060201公开号:EP1848746A2公开日:20071031
摘要:A purification process for the capsular polysaccharide of S.agalactiae in whichthe saccharide is initially treated with an aqueous mixture of an alcohol and a calcium salt,followed by precipitation with a cationic detergent. The process can be completed in lessthan three days and has a yield of around 60%. It avoids the need for DNase, RNaseand/or protease treatment. The saccharides of the process have a very low proteincontamination and a very low absorbance at 280nm.
申请人:Novartis Vaccines and Diagnostics S.r.l.
地址:Via Fiorentina 1 53100 Siena (SI) IT
国籍:IT
代理机构:Marshall, Cameron John
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