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PURIFICATION OF STREPTOCOCCAL CAPSULAR POLYSACCHAR

2022-05-22 来源:客趣旅游网
专利内容由知识产权出版社提供

专利名称:PURIFICATION OF STREPTOCOCCAL

CAPSULAR POLYSACCHARIDE

发明人:COSTANTINO, PAOLO申请号:EP06710574.2申请日:20060201公开号:EP1848746A2公开日:20071031

摘要:A purification process for the capsular polysaccharide of S.agalactiae in whichthe saccharide is initially treated with an aqueous mixture of an alcohol and a calcium salt,followed by precipitation with a cationic detergent. The process can be completed in lessthan three days and has a yield of around 60%. It avoids the need for DNase, RNaseand/or protease treatment. The saccharides of the process have a very low proteincontamination and a very low absorbance at 280nm.

申请人:Novartis Vaccines and Diagnostics S.r.l.

地址:Via Fiorentina 1 53100 Siena (SI) IT

国籍:IT

代理机构:Marshall, Cameron John

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