Peptide vaccines for cancers expressing tumor-asso

专利名称：Peptide vaccines for cancers expressing

tumor-associated antigens

发明人：Takuya Tsunoda,Ryuji Ohsawa申请号：US14079144申请日：20131113公开号：US09067973B2公开日：20150630

摘要：The present invention provides peptides having an amino acid sequence as setforth in SEQ ID NO: 19, 22, 30, 34, 344, 358, 41, 44, 46, 48, 78, 376, 379, 80, 100, 101, 110,111, 387, 112, 394, 114, 116, 117, 121, 395, 133, 135, 137, 426, 143, 147, 148, 149, 150, 152,153, 154, 156, 160, 161, 162, 163, 166, 174, 178, 186, 194, 196, 202, 210, 213, 214, 217, 223,227, 228, 233, 254, 271, 272 or 288, as well as peptides having the above-mentioned aminoacid sequences in which 1, 2, or several (e.g., up to 5) amino acids are substituted, deleted,or added, provided the peptides possess cytotoxic T cell inducibility. The presentinvention also provides drugs for treating or preventing a disease associated with over-expression of the CDH3, EPHA4, ECT2, HIG2, INHBB, KIF20A, KNTC2, TTK and/or URLC10,e.g. cancers containing as an active ingredient one or more of these peptides. Thepeptides of the present invention find further utility as vaccines.

申请人：ONCOTHERAPY SCIENCE, INC.

地址：Kanagawa JP

国籍：JP

代理机构：Kilpatrick Townsend & Stockton LLP

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