专利名称：Small molecule therapeutic compounds
targeting thioesterase deficiency disordersand methods of using the same
发明人：Anil Baran Mukherjee,Chinmoy
Sarkar,Zhongjian Zhang
申请号：US14110393申请日：20120409公开号：US09629816B2公开日：20170425
摘要：The invention provides methods of inhibiting the development or progressionof a thioesterase deficiency disorder in a mammal by the administration of a compoundthat functionally mimics the enzymatic activity of all thioesterases in mammals. Suchthioesterase deficiency disorders include cancers and adult- or infant-neuronal ceroidlipofuscinoses (NCLs). The invention also provides small molecule mimics of thioesterasesuseful in the methods of the invention and pharmaceutical compositions containing thetherapeutically effective compounds and methods of using the same.
申请人：Anil Baran Mukherjee,Chinmoy Sarkar,Zhongjian Zhang
地址：Brookeville MD US,Rockville MD US,Rockville MD US
国籍：US,US,US
代理机构：Sheridan Ross P.C.
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