专利名称：Viral vector
发明人：JAMES E. MISKIN,FRASER J. WILKES,PHILIPPA
RADCLIFFE,KYRIACOS A. MITROPHANOUS
申请号：AU2003238456申请日：20030203
公开号：AU2003238456A1公开日：20030902
摘要：A multicistronic retroviral vector genome comprising a first nucleic acidsequence upstream of an internal regulatory element, such that the level of genomicRNA available for packaging in the absence of rev, or a functional equivalent thereof, isincreased. The internal regulatory element can be a promoter or an ires (internalribosome entry sequence)
申请人：OXFORD BIOMEDICA (UK) LIMITED
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