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Liposomal mitigation of drug-induced inhibition of

2022-06-06 来源:客趣旅游网
专利内容由知识产权出版社提供

专利名称:Liposomal mitigation of drug-induced

inhibition of the cardiac ikr channel

发明人:Lawrence Helson,George M. Shopp,Annie

Bouchard

申请号:US15403831申请日:20170111公开号:US10349884B2公开日:20190716

摘要:Compositions and methods are provided for preventing one or more cardiacchannelopathies or conditions resulting from irregularities or alterations in cardiacpatterns, or both, in a human or animal subject comprising: one or more

pharmacologically active agents that causes at least one of Ichannel inhibition or QTprolongation by inhibiting the activity of an ether-a-go-go-related gene (hERG); and oneor more liposomes, wherein the liposomes are empty liposomes and administered priorto, concomitantly, or after administration of the pharmacologically active agent.

申请人:SignPath Pharma Inc.

地址:Quakertown PA US

国籍:US

代理机构:Chalker Flores, LLP

代理人:Edwin S. Flores

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